Many people who suffer from pancreatitis use cannabis in some form for such as cannabis oil or they smoke weed (Marijuana) for relief of symptoms such as intractable pain and nausea yet a word of caution …
There is an inherent risk of Cannabinoid Hyperemesis Syndrome or CHS [1,2,3] due to a poison called Azadirachtin [4,5]. Azadirachtin is found in the seeds of the Neem tree, Azadirachta indica (Neem Oil) and is used as an organic pesticide.
Cannabinoid Hyperemesis Syndrome Symptoms
The symptoms of CHS can be awfully nasty. You probably won’t die (yet there have been cases in India that ended in death) but you might think you are on your way out. Seek emergency treatment!
- Abdominal pain, often severe
- Extreme nausea
- Vomiting, often intractable
- Rapid breathing, tachypnea with acidotic respiration
Symptoms that could prove deadly
- Organ involvement, failure
Antidote and Emergency Treatment
You can read this exact quote here, again this article, section 12.1.1:
Gastrointestinal decontamination: Due to the severe gastrointestinal irritation, gastric emptying and catharsis are not indicated. Consideration should be given to administration of activated charcoal …U.S. Environmental Protection Agency/Office of Prevention, Pesticides, and Toxic Substances. Reigart, J.R., Roberts, J.R. Recognition and Management of Pesticide Poisonings. 5th ed. 1999. EPA Document No. EPA 735-R-98-003, and available in electronic format at: http://www.epa.gov/pesticides/safety/healthcare , p. 63
If this insecticide is safe for humans why is there an antidote and emergency treatment section of a government document?
Most of the info from agriculture circles will tell you that Azadirachtin is safe .
But is it really?
Here is an excerpt of one article section 12.1.2 called “human toxicity excerpts” published by the National Institute of Health, NIH:
Human Toxicity Excerpts
/SIGNS AND SYMPTOMS/ Neem seed oil produced occasional diarrhea, nausea, and general discomfort when given orally as an anthelmintic. /Neem seed oil/
Krieger, R. (ed.). Handbook of Pesticide Toxicology. Volume 1, 2nd ed. 2001. Academic Press, San Diego, California., p. 132
/SIGNS AND SYMPTOMS/ … 13, including 2 fatal, poisoning cases due to neem seed (margosa) oil, a traditional remedy in India and Malaysia, /were reported/. Five to ten milliliters of the oil given orally to children against minor ailments caused vomiting, drowsiness, tachypnea with acidotic respiration, and polymorphonuclear leukocytosis, and encephalopathy developed within hours of ingestion. Seizures, associated with coma, developed in some cases. Autopsy demonstrated pronounced fatty acid infiltration of the liver and proximal renal tubules, with mitochondrial damage, and cerebral edema, changes consistent with Reye’s syndrome. Krieger, R. (ed.). Handbook of Pesticide Toxicology. Volume 1, 2nd ed. 2001. Academic Press, San Diego, California., p. 132
And here’s the scary part about CHS: The vomiting is often intractable. Even powerful antiemetics such as
1) Cannabinoid Hyperemesis Syndrome – read here
2) Cannabinoid hyperemesis – read here
3) Marijuana use may cause severe cyclic nausea, vomiting, a little-known, but costly effect – read here
4) Azadirachtin A – read here
5) Azadirachtin – read here
6) How to Get Over It: Fear of Vomiting – read here